Bimanual digit training improves right-hand dexterity in older adults by reactivating declined ipsilateral motor-cortical inhibition
| Autor: | Satoshi Hirose, Chikako Kamimukai, Nodoka Kimura, Minoru Asada, Eiichi Naito, Hideya Okamoto, Tomoyo Morita |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Physiology Movement Science Aging society Functional Laterality Article Fingers Young Adult Physical medicine and rehabilitation Developmental biology medicine Humans Psychology Single-Blind Method Exercise Aged Brain Mapping Multidisciplinary medicine.diagnostic_test business.industry Motor Cortex Magnetic Resonance Imaging Numerical digit Inhibition Psychological Motor Skills Medicine Female Cortical inhibition Functional magnetic resonance imaging business Neuroscience |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021) Scientific Reports |
| DOI: | 10.1101/2021.05.21.445083 |
| Popis: | Improving deteriorated sensorimotor functions in older individuals is a social necessity in a super-aging society. Previous studies suggested that the declined interhemispheric sensorimotor inhibition observed in older adults is associated with their deteriorated hand/finger dexterity. Here, we examined whether bimanual digit exercises, which can train the interhemispheric inhibitory system, improve deteriorated hand/finger dexterity in older adults. Forty-eight healthy, right-handed, older adults (65–78 years old) were divided into two groups, i.e., the bimanual (BM) digit training and right-hand (RH) training groups, and intensive daily training was performed for 2 months. Before and after the training, we evaluated individual right hand/finger dexterity using a peg task, and the individual state of interhemispheric sensorimotor inhibition by analyzing ipsilateral sensorimotor deactivation via functional magnetic resonance imaging when participants experienced a kinesthetic illusory movement of the right-hand without performing any motor tasks. Before training, the degree of reduction/loss of ipsilateral motor-cortical deactivation was associated with dexterity deterioration. After training, the dexterity improved only in the BM group, and the dexterity improvement was correlated with reduction in ipsilateral motor-cortical activity. The capability of the brain to inhibit ipsilateral motor-cortical activity during a simple right-hand sensory-motor task is tightly related to right-hand dexterity in older adults. |
| Databáze: | OpenAIRE |
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