Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
| Autor: | Feng Lan, Rui Guo, Tian Feng, Dehua Chang, Masatoshi Morimatsu, Feng Wan, Yunpeng Ling |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Swine Medicine (miscellaneous) Heart failure Review 030204 cardiovascular system & hematology Mesenchymal Stem Cell Transplantation Biochemistry Genetics and Molecular Biology (miscellaneous) Cell therapy lcsh:Biochemistry 03 medical and health sciences 0302 clinical medicine Tissue engineering Pluripotent stem cells Medicine Animals Humans lcsh:QD415-436 Myocardial infarction Induced pluripotent stem cell Skeletal myoblasts Cardiac tissue Inflammation lcsh:R5-920 Tissue Engineering business.industry Myocardium Mesenchymal stem cell Cell Biology medicine.disease Rats Transplantation 030104 developmental biology Molecular Medicine Mesenchymal stem cells Angiogenesis Stem cell business lcsh:Medicine (General) Cell sheet |
| Zdroj: | Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020) Stem Cell Research & Therapy |
| ISSN: | 1757-6512 |
| Popis: | Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and scaffold tissue engineering. Furthermore, induced pluripotent stem cell-derived cell sheets have been indicated to possess higher potential for MI therapy than other stem cell-derived sheets because of their capacity to form vascularized networks for fabricating thickened human cardiac tissue and their long-term therapeutic effects after transplantation in MI. To date, stem cell sheet transplantation has exhibited a dramatic role in attenuating cardiac dysfunction and improving clinical manifestations of heart failure in MI. In this review, we retrospectively summarized the current applications and strategy of stem cell-derived cell sheet technology for heart tissue repair in MI. |
| Databáze: | OpenAIRE |
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