An immunostimulating water insoluble β-glucan of an edible hybrid mushroom: Isolation and characterization
| Autor: | Swatilekha Maiti, Kousik Maity, Saikat Maity, Samir R. Sikdar, Surajit Samanta, Syed S. Islam, Tapas K. Maiti, Ipsita K. Sen, Birendra Behera, Sunil K. Bhanja |
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| Rok vydání: | 2013 |
| Předmět: |
Magnetic Resonance Spectroscopy
beta-Glucans Polysaccharide Mice Hydrolysis Drug Discovery Carbohydrate Conformation Splenocyte Animals Fruiting Bodies Fungal Cells Cultured Glucan Pharmacology chemistry.chemical_classification Pleurotus Mushroom Thymocytes biology food and beverages General Medicine biology.organism_classification Somatic fusion Biochemistry chemistry Macrophages Peritoneal Carbohydrate Metabolism Agaricales Two-dimensional nuclear magnetic resonance spectroscopy Spleen |
| Zdroj: | Fitoterapia. 84:15-21 |
| ISSN: | 0367-326X |
| DOI: | 10.1016/j.fitote.2012.10.014 |
| Popis: | An immunostimulating water-insoluble β-glucan isolated from hot alkaline extract of the fruiting bodies of an edible somatic hybrid mushroom of Pleurotus florida and Calocybe indica var. APK2 showed significant macrophage, splenocyte, and thymocyte activations. On the basis of total hydrolysis, methylation analysis, and NMR experiments (1H, 13C, DQF-COSY, TOCSY, NOESY, DEPT-135, and HSQC), the repeating unit of the polysaccharide is established. |
| Databáze: | OpenAIRE |
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