New Developments in Insulin Therapy for Type 2 Diabetes
| Autor: | Christopher Sorli |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Self Administration Type 2 diabetes Weight Gain Injections Medication Adherence Absorption rate Drug Delivery Systems Internal medicine Humans Hypoglycemic Agents Insulin Medicine Disease process Intensive care medicine Clinical Trials as Topic business.industry Treatment regimen Therapies Investigational Basal insulin Disease Management General Medicine medicine.disease Hypoglycemia Endocrinology Diabetes Mellitus Type 2 Drug Monitoring business Insulin products Healthcare providers |
| Zdroj: | The American Journal of Medicine. 127:S39-S48 |
| ISSN: | 0002-9343 |
| DOI: | 10.1016/j.amjmed.2014.07.006 |
| Popis: | Insulin has classically been considered a treatment of last resort for individuals with type 2 diabetes, delayed until all other efforts by the patient and healthcare provider have failed. Recent treatment guidelines recommend the use of insulin, in particular basal insulin, as part of a treatment regimen earlier in the disease process. Many patients are reticent about initiating insulin, so therapies that allow insulin treatment to be more tailored to individual needs are likely to result in greater acceptance and patient adherence with therapy. To meet this need, a range of insulin products are in development that aim to increase absorption rate or prolong the duration of action, reduce peak variability and weight gain associated with insulin treatment, and offer alternative delivery methods. This review describes insulin products in clinical development, new combination therapies, and new devices for insulin delivery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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