Posterior reversible leukoencephalopathy syndrome: Case series and review of the literature

Autor: Alejandro Alvarellos, María Victoria Borghi, M. Colazo, Soledad Retamozo, Juan Pablo Pirola, María Jezabel Haye Salinas, N. Benzaquén, Francisco Caeiro, Ana Cecilia ÿlvarez, Verónica Saurit, Cecilia Lucero, Diego Federico Baenas
Rok vydání: 2017
Předmět:
Zdroj: Reumatologia clinica. 16(2 Pt 2)
ISSN: 2173-5743
Popis: Objective To describe clinical manifestations, antecedents, comorbidities and associated treatments, imaging findings, and follow-up in patients with posterior reversible encephalopathy syndrome. Methods A retrospective, descriptive analysis of admitted patients was performed between June 2009 and May 2014 in a third-level care hospital. We evaluated age, sex, comorbidities, symptoms, values of blood pressure at admission, renal function, medication and time elapsed until the disappearance of symptoms. Results Thirteen patients were included. In all, 77% of them had a history of hypertension at baseline and 85% had impaired renal function. The most prevalent comorbidity was renal transplantation, and 85% had deterioration of renal function. Five of the patients had undergone renal transplantation. The most common clinical manifestation was seizures. All had subcortical lesions and bilateral parietooccipital involvement was the finding most frequently observed. Conclusion This syndrome should be taken into account in the differential diagnoses of patients presenting with acute neurological syndromes and the abovementioned risk factors.
Databáze: OpenAIRE