Vital Staining with Alizarin in Clinical Malignant Conditions of Bone
| Autor: | A. Laufer, S. Schorr, I. Aviad |
|---|---|
| Rok vydání: | 1959 |
| Předmět: |
Rubia tinctorum
Pathology medicine.medical_specialty chemistry.chemical_element Anthraquinones Bone Neoplasms Calcium Alizarin Stain Bone and Bones chemistry.chemical_compound Neoplasms medicine Radiology Nuclear Medicine and imaging Coloring Agents Staining and Labeling biology Ossification business.industry Selective staining Anatomy biology.organism_classification Staining chemistry Vital stain sense organs medicine.symptom business |
| Zdroj: | Radiology. 73:410-417 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/73.3.410 |
| Popis: | Madder, or Rubia tinctorum, is a plant which has been known for centuries. A marked staining of the growing ends of all bones in young animals was obtained with madder. The teeth were stained at their roots. In 1736 Belchier (1) noted that bones of cooked pork had a reddish tinge, assuming, correctly, that madder was the factor that reddened the bones of the pigs. Duhamel (4), in 1739, introduced the coloring of growing bone with madder in ossification studies. Alizarin was recognized as the principal staining ingredient of the plant in 1826, by Robiquet and Colin (11). In 1869 alizarin was synthesized. Gottlieb (6), in 1914, expressed the belief that alizarin has a specific chemical affinity for calcium. According to Cameron (1930) the tinctorial effect in the hard tissues is due to the property of alizarin to form a dye-lake with calcium, for which it is nearly a specific stain. Schour et al. (12) (1941) state that alizarin has a selective staining effect upon the calcifying or calcioreceptive zone of t... |
| Databáze: | OpenAIRE |
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