Sodium sulphide promoted synthesis of fused quinoline at room temperature

Autor:	Vishal Prasad Sharma, Ashish Kumar Tewari, Radhey M. Singh, Rashmi Singh, Priyanka Sonker, Priyanka Yadav
Rok vydání:	2021
Předmět:	chemistry.chemical_classification Annulation Organic Chemistry Quinoline Temperature chemistry.chemical_element Salt (chemistry) Sulfides Biochemistry Sulfur Catalysis chemistry.chemical_compound chemistry Sodium sulphide Quinolines Organic chemistry Physical and Theoretical Chemistry
Zdroj:	Organic & Biomolecular Chemistry. 19:8108-8112
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d1ob01085a
Popis:	A novel, simple and eco-friendly strategy for the synthesis of thiopyrano[4,3-b]quinolin-1-ones and pyrrolo[3,4-b]quinolin-1-ones from 2-alkynylquinoline-3-carbonitriles and sodium sulphide (Na2S·9H2O) under catalyst-free conditions at room temperature has been described. In this reaction, a readily available inorganic salt (Na2S·9H2O) serves as the sulphur source and leads to the generation of diverse functionalized thiopyrano[4,3-b]quinolin-1-ones and pyrrolo[3,4-b]quinolin-1-ones in moderate to excellent yields through sulfuration, annulation, and aerial oxidation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de07741a75f18a53a439a1468c8f94a4 https://doi.org/10.1039/d1ob01085a Zobrazit plný text záznamu