Synthetic studies on borrelidin: enantioselective synthesis of the C1-C12 fragment

Autor:	Sunny Abraham, and Alan X. Xiang, Binh G. Vong, Emmanuel A. Theodorakis
Rok vydání:	2003
Předmět:	Alkylation Stereochemistry Chemistry Organic Chemistry Enantioselective synthesis Stereoisomerism Biochemistry Anti-Bacterial Agents Fragment (logic) Chain (algebraic topology) Indicators and Reagents Macrolides Physical and Theoretical Chemistry Fatty Alcohols
Zdroj:	Organic letters. 5(10)
ISSN:	1523-7060
Popis:	[structure: see text] An efficient, enantioselective synthesis of the C1-C12 fragment 2 of borrelidin is presented. Construction of the "skipped" polymethylene chain of 2 was accomplished by iteration of Myers' alkylation, while formation of the C3 stereocenter was achieved by Roush's asymmetric allylboration methodology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf6283b06ebc8abdd67d5b4f28deaff https://pubmed.ncbi.nlm.nih.gov/12735735 Zobrazit plný text záznamu