Clinical and laboratory studies of plasma thromboplastin antecedent deficiency (PTA)
| Autor: | Robert L. Wall, John A. Cavins |
|---|---|
| Rok vydání: | 1960 |
| Předmět: |
medicine.medical_specialty
Factor XI Deficiency business.industry Research PTA deficiency General Medicine Hemorrhagic Disorders medicine.disease_cause Penetrance Gastroenterology Hemorrhagic disorder Surgery Internal medicine Heredity medicine Plasma thromboplastin antecedent deficiency Humans business Factor XI |
| Zdroj: | The American Journal of Medicine. 29:444-448 |
| ISSN: | 0002-9343 |
| DOI: | 10.1016/0002-9343(60)90040-1 |
| Popis: | Fourteen patients with PTA deficiency are reviewed, including a family with six bleeders in the past two generations. Data are presented which show that the bleeding tendency in this disorder is often mild, as hitherto emphasized, but may also be of moderate or severe degree. Heredity appears to be by an autosomal dominant gene with variable expressivity and incomplete penetrance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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