| Autor: |
Bruce L. Miller, Markus Britschgi, David S. Knopman, Zachary A. Miller, Steve Younkin, Hudson Johns, Chung-Huan Sun, Tony Wyss-Coray, Ronald C. Petersen, Ruo-Pan Huang, Michael D. Leipold, Eva Czirr, Gabriela K. Fragiadakis, Anna Karydas, Philipp A. Jaeger, Holden T. Maecker, Adam L. Boxer, Neill R. Graff-Radford, Trisha Stan, Daniela Berdnik, Ruochun Huang, Rosa Rademakers, Bradley F. Boeve, Nicole A. Finch |
| Rok vydání: |
2016 |
| Předmět: |
|
| DOI: |
10.1101/049791 |
| Popis: |
The growing link between systemic environment and brain function opens the possibility that cellular communication and composition in blood are correlated with brain health. We tested this concept in frontotemporal dementia with novel, unbiased tools that measure hundreds of soluble signaling proteins or characterize the vast immune cell repertoire in blood. With these tools we discovered complementary abnormalities indicative of abnormal T cell populations and autoimmunity in frontotemporal dementia. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
