Electric field-navigated transcranial magnetic stimulation for chronic tinnitus: a randomized, placebo-controlled study
| Autor: | Jaakko Salonen, Janika Paavola, Noora Sjösten, Satu K. Jääskeläinen, Tero Taiminen, Anu Holm, Eliisa Löyttyniemi, Katri Niinivirta-Joutsa, Juho Joutsa, Hanna Sahlsten, Reijo Johansson, Esa Rauhala, Juuso Virtanen |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Linguistics and Language medicine.medical_specialty medicine.medical_treatment Chronic tinnitus Placebo-controlled study Controlled studies Audiology Placebo ta3112 Language and Linguistics Tinnitus Young Adult 03 medical and health sciences Speech and Hearing 0302 clinical medicine otorhinolaryngologic diseases medicine Humans Prospective Studies 030223 otorhinolaryngology Aged Middle Aged Transcranial Magnetic Stimulation ta3125 Transcranial magnetic stimulation Distress Female medicine.symptom Psychology 030217 neurology & neurosurgery After treatment |
| Zdroj: | International Journal of Audiology. 56:692-700 |
| ISSN: | 1708-8186 1499-2027 |
| Popis: | Repetitive transcranial magnetic stimulation (rTMS) may alleviate tinnitus. We evaluated effects of electric field (E-field) navigated rTMS targeted according to tinnitus pitch. No controlled studies have investigated anatomically accurate E-field-rTMS for tinnitus.Effects of E-field-rTMS were evaluated in a prospective randomised placebo-controlled 6-month follow-up study on parallel groups. Patients received 10 sessions of 1 Hz rTMS or placebo targeted to the left auditory cortex corresponding to tonotopic representation of tinnitus pitch. Effects were evaluated immediately after treatment and at 1, 3 and 6 months. Primary outcome measures were visual analogue scores (VAS 0-100) for tinnitus intensity, annoyance and distress, and the Tinnitus Handicap Inventory (THI).Thirty-nine patients (mean age 50.3 years).The mean tinnitus intensity (FDespite the significant effects of rTMS on tinnitus, differences between active and placebo groups remained non-significant, due to large placebo-effect and wide inter-individual variation. |
| Databáze: | OpenAIRE |
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