88. Comparison results of different strategies of radiotherapy in nasopharyngeal carcinoma
Autor: | M. Matecka-Nowak, Piotr Milecki, G. Stryczyńska, E. Adamiak, A. Kruk-Zagajewska, D. Fundowicz |
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Rok vydání: | 2001 |
Předmět: |
medicine.medical_specialty
Cancer Research business.industry medicine.medical_treatment Comparison results medicine.disease Surgery Radiation therapy Nasopharyngeal carcinoma Oncology Radiology Nuclear Medicine and imaging Total dose medicine Radiology Nuclear Medicine and imaging Radiology business |
Zdroj: | Reports of Practical Oncology & Radiotherapy. 6(1):67-68 |
ISSN: | 1507-1367 |
DOI: | 10.1016/s1507-1367(01)70458-0 |
Popis: | Aim : Evaluation results of radiotherapy in nasopharyngeal carcinoma in years; 1980–1990 (before CT era) vs 1991–1995. Material/methods : One hundred eighty eight patients treated in our centre were included in this analysis. Two groups of patients were distinguished: I-st – 128 patients (treated between 1980–1990) and II-nd – 60 (treated between 1991–1995). The possibilities of diagnosis and radiotherapy techniques were diffrent in both groups. In the II-nd group; the shrinking field technique, CT in diagnosis and target delineation and also higher total dose (mean 66 Gy) were applied. Results : For all patients 5-years disease free-survival was 30%. During follow-up the first two years were crucial, because 80% of failures occured. The causes of failures were as follow: the local recurrence (43%), metastases to lymph nodes (39%) and distant metastases (18%). Conclusions : Introducing CT into diagnosis and target delineation, the shrinking field technique and higher total dose of irradiation caused in improvement of results of radiotherapy in nasopharyngeal carcinoma. |
Databáze: | OpenAIRE |
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