A controlled study of the long-term prognosis of adult still's disease
| Autor: | Simon Carette, John S. Sampalis, James F. Fries, Andrzej Gutkowski, John M. Esdaile, François Beaudet, Daniel Myhal, Jean Luc Senécal, Alison J. Partridge, Manfred Harth, John J. Cush, Carol Yeadon, Thomas A. Medsger |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Gerontology Physical disability Adolescent Occupational prestige Disease Family income Social support Social skills Risk Factors medicine Humans Disabled Persons Sibling Adult Still's disease business.industry General Medicine Middle Aged Prognosis medicine.disease Treatment Outcome Case-Control Studies Multivariate Analysis Female business Still's Disease Adult-Onset |
| Zdroj: | The American Journal of Medicine. 98:384-388 |
| ISSN: | 0002-9343 |
| DOI: | 10.1016/s0002-9343(99)80318-0 |
| Popis: | purpose To assess the long-term prognosis of patients with adult Still's disease for physical and psychological disability, pain, social functioning, social support, medication use, formal education, occupation, time lost from work, and family income, and to contrast these results with those of same-sex sibling controls. patients and methods Patients were recruited from medical center-based cohorts in Pittsburgh and Eastern Canada and from a national survey of rheumatologists. Patients and same-sex sibling controls completed the Health Assessment Questionnaire for physical disability, the psychological and social function domains of the Arthritis Impact Measurement Scales, and the Interpersonal Skills Evaluation List questionnaire for social support, and replied to questions on medication use, formal education, occupation, time lost from work, and family income. results One hundred four of 111 eligible adult Still's patients (94%) provided data. They identified 86 same-sex sibling controls, of whom 60 (70%) participated. The mean duration of adult Still's disease was 10 years. Approximately half of patients continued to require medication even 10 years after diagnosis. Patients had significantly higher levels of pain, physical disability, and psychological disability when compared with the controls. However, the levels of pain and physical disability were low compared to patients with other rheumatic diseases. Educational achievement, occupational prestige, social functioning and support, time lost from work, and family income were similar for both patients and controls. conclusions Despite causing disability, pain, and, in many, the need for long-term medication, patients with adult Still's disease are resilient. The disease did not interfere with educational attainment, occupational prestige, social functioning and support, time lost from work, or family income. |
| Databáze: | OpenAIRE |
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