Purunusides A-C, α-glucosidase inhibitory homoisoflavone glucosides from Prunus domestica
| Autor: | Itrat Fatima, Muhammad Iqbal Chouhdary, Sumaira Talib, Azhar Mahmood, Abdul Malik, Shaheen Kosar, Rehana Ahmed |
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| Rok vydání: | 2009 |
| Předmět: |
Magnetic Resonance Spectroscopy
Spectrophotometry Infrared Rosaceae Chemical structure Molecular Conformation Ethyl acetate Prunus chemistry.chemical_compound Glucosides Drug Discovery Glycoside Hydrolase Inhibitors Enzyme Inhibitors chemistry.chemical_classification biology Organic Chemistry Isoflavones biology.organism_classification Enzyme chemistry Biochemistry Alpha-glucosidase Shoot Solvents biology.protein Molecular Medicine Spectrophotometry Ultraviolet Chromatography Thin Layer Plant Shoots |
| Zdroj: | Archives of Pharmacal Research. 32:1705-1710 |
| ISSN: | 1976-3786 0253-6269 |
| DOI: | 10.1007/s12272-009-2207-9 |
| Popis: | Purunusides A-C (1-3), new homoisoflavone glucosides together with the known compounds beta-sitosterol (4) and 6,7-methylenedioxy-8-methoxycoumarin (5) have been isolated from n-butanol and ethyl acetate soluble fractions of Prunus domestica. Their structures were assigned on the basis of spectral studies. The compounds 1-3 showed potent inhibitory activity against the enzyme alpha-glucosidase. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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