Langerhans cell histiocytosis: Presentation in a preterm neonate
| Autor: | Shaily P Patel, Ana Fadhel Alvarez, Jaclyn E Ruggiero, Chiamaka Aneji, Maya I Brasher |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Cancer Research
Systemic disease Pathology medicine.medical_specialty congenital rash Disease Langerhans‐cell histiocytosis Diagnosis Differential Fatal Outcome Langerhans cell histiocytosis medicine Humans neonatal prematurity RC254-282 Skin Findings business.industry Infant Newborn Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Tumor formation Organ damage Histiocytosis Langerhans-Cell Oncology Immunohistochemistry Presentation (obstetrics) business Infant Premature |
| Zdroj: | Cancer Reports, Vol 5, Iss 2, Pp n/a-n/a (2022) |
| ISSN: | 2573-8348 |
| Popis: | Background Langerhans cell histiocytosis (LCH) is a rare disorder in which Langerhans cells (LC) accumulate in the skin or other organs and cause tumor formation or organ damage. Cutaneous lesions can vary widely and do not predict extent of systemic disease or prognosis. Case We present a premature infant with skin findings, multisystem involvement, and immunohistochemical markers consistent with multisystem LCH. Conclusion Limited data from preterm neonates with LCH suggest that prognosis is particularly poor, with even limited cutaneous disease often rapidly progressing to become fatal, although diagnosis is not always prompt. Early diagnosis and treatment may affect prognosis. |
| Databáze: | OpenAIRE |
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