Contribution of immunodiagnostic tests to epidemiological/intervention studies of cysticercosis/taeniosis in Mexico
| Autor: | Ana Flisser, T. W. Gyorkos |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Veterinary medicine Swine Immunology Neurocysticercosis Enzyme-Linked Immunosorbent Assay Immunologic Tests Feces Seroepidemiologic Studies Environmental health parasitic diseases Taenia solium Medicine Animals Humans Mexico biology business.industry Transmission (medicine) Cysticercosis Public health medicine.disease biology.organism_classification medicine.drug_formulation_ingredient Antigens Helminth Taenia Parasitology Health education business |
| Zdroj: | Parasite immunology. 29(12) |
| ISSN: | 0141-9838 |
| Popis: | Cysticercosis is acquired when swine ingest human faeces contaminated with Taenia solium eggs. Humans become tapeworm carriers when they ingest infected pork meat. They can also develop cysticercosis after inadvertently swallowing T. solium eggs. Human neurocysticercosis (NCC) is considered as a public health problem in Mexico and in several countries around the world, mainly developing ones. The development of immunodiagnostic techniques has promoted the conduct of seroepidemiological studies. This review provides insight into the evolution of these techniques, their predictive values and their use in field studies, and summarizes evidence supporting health care practice and policy related to cysticercosis/taeniosis in Mexico. Serological studies in rural and urban settings have demonstrated that close proximity with a tapeworm carrier is the main risk factor for acquiring cysticercosis. Research focusing on the tapeworm carrier generated an ELISA for the detection of Taenia coproantigens and facilitated the evaluation of intervention measures. Health education and self-identification of tapeworm carriers were shown to be successful. However, cestodial treatment as a community-based intervention was not as successful. Current immunodiagnostic techniques can be used to pinpoint transmission foci so that appropriate and effective interventions can be applied. In this way, sustainable control, and even eradication of T. solium may be envisioned. |
| Databáze: | OpenAIRE |
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