Endoscopic cryotherapy for the treatment of bleeding mucosal vascular lesions of the GI tract: A pilot study
| Autor: | Anthony N. Kalloo, Marcia R. Cruz-Correa, Pankaj J. Pasricha, Cheryl A. Vaughn, Sanjay B. Jagannath, Sergey V. Kantsevoy |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Pilot Projects Cryotherapy Gastroenterology Arteriovenous Malformations Internal medicine medicine Humans Proctitis Radiology Nuclear Medicine and imaging Radiation Injuries Aged business.industry Vascular disease Stomach Hemostasis Endoscopic Gastric antral vascular ectasia Arteriovenous malformation medicine.disease Surgery medicine.anatomical_structure Gastritis Duodenum Female medicine.symptom Gastrointestinal Hemorrhage business Gastric Antral Vascular Ectasia |
| Zdroj: | Gastrointestinal Endoscopy. 57:403-406 |
| ISSN: | 0016-5107 |
| DOI: | 10.1067/mge.2003.115 |
| Popis: | Background: Thermal therapy is the cornerstone of endoscopic treatment of bleeding mucosal lesions of the GI tract. However, there is a 20% failure rate and contact devices may be cumbersome in the treatment of large bleeding areas. A pilot study was conducted to evaluate the safety and efficacy of endoscopic cryotherapy for bleeding mucosal vascular lesions. Methods: Patients with recurrent bleeding from diffuse mucosal vascular lesions were treated with cryotherapy and had endoscopic and clinical follow-up. Results: Twenty-six patients with gastric and duodenal arteriovenous malformations (n = 7), watermelon stomach (n = 7), radiation-induced gastritis (n = 5), and radiation-induced proctitis (n = 7) were treated with mean of 3.4 (1.6) sessions. The best results were achieved in patients with radiation-induced proctitis, with cessation of bleeding in all 7 patients. Cryotherapy was also effective in patients with multiple arteriovenous malformations (86%) and watermelon stomach (71%). It was less effective in patients with radiation-induced damage to stomach and duodenum, although all patients in this group were debilitated because of disseminated malignancy. Conclusions: Cryotherapy is a safe and effective treatment for bleeding from diffuse mucosal lesions of the GI tract. Bleeding from radiation-induced proctitis and multiple arteriovenous malformations is particularly responsive to endoscopic cryotherapy. |
| Databáze: | OpenAIRE |
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