Epidemiology of nosocomial infections in selected neonatal intensive care units in Colombia, South America

Autor: Angela Leon, Hernan Cruz, Carl L. Bose, Meica M. Efird, Juan G. Piñeros, Guillermo Robayo, Maria E. Gosendi, Catherine Rojas, Angeles Hoyos, Mario A. Rojas, Juan Manuel Lozano, María Ximena Rojas, Martín Rondón, Gloria Ruiz
Rok vydání: 2005
Předmět:
Zdroj: Journal of perinatology : official journal of the California Perinatal Association. 25(8)
ISSN: 0743-8346
Popis: The epidemiology of nosocomial infections (NI) in neonatal intensive care units in developing countries has been poorly studied. We conducted a prospective study in selected neonatal units in Colombia, SA, to describe the incidence rate, causative organisms, and interinstitutional differences. Data were collected prospectively from February 20 to August 30, 2001 from eight neonatal units. NI was defined as culture-proven infection diagnosed after 72 h of hospitalization, resulting in treatment with antibiotics for >3 days. Linear regression models were used to describe associations between institutional variables and NI rates. A total of 1504 infants were hospitalized for more than 72 h, and therefore, at risk for NI. Of all, 127 infections were reported among 80 patients (5.3%). The incidence density rate was 6.2 per 1000 patient-days. Bloodstream infections accounted for 78% of NIs. Gram-negative organisms predominated over gram-positive organisms (55 vs 38%) and were prevalent in infants ≤2000 g (54%). The most common pathogens were Staphylococcus epidermidis (26%) and Klebsiella pneumonia (12%). Gram-negative organisms predominate in Colombia among infants
Databáze: OpenAIRE