Impact of a Family Clinic Day intervention on paediatric and adolescent appointment adherence and retention in antiretroviral therapy: A cluster randomized controlled trial in Uganda

Autor: Esther Mirembe, Sarah A. Moberley, Christine J. Schellack, Marta R. Prescott, Peter Elyanu, Betty Mirembe, Barbara Asire, Joshua Musinguzi, Ivan Lukabwe, Margaret L. Prust, Justin C. Graves
Jazyk: angličtina
Rok vydání: 2018
Předmět:
0301 basic medicine
Male
RNA viruses
lcsh:Medicine
HIV Infections
Peer support
Adolescents
Pathology and Laboratory Medicine
Ambulatory Care Facilities
Pediatrics
law.invention
Geographical Locations
Families
0302 clinical medicine
Randomized controlled trial
Immunodeficiency Viruses
law
Outcome Assessment
Health Care

Medicine and Health Sciences
Medicine
Uganda
Public and Occupational Health
030212 general & internal medicine
Young adult
Child
lcsh:Science
Health Education
Children
Multidisciplinary
Child Health
Health Education and Awareness
Medical Microbiology
Child
Preschool

Viral Pathogens
Viruses
Health education
Female
Pathogens
Research Article
medicine.medical_specialty
Adolescent
Patients
Anti-HIV Agents
MEDLINE
Disease cluster
Microbiology
03 medical and health sciences
Appointments and Schedules
Young Adult
Intervention (counseling)
Retroviruses
Humans
Microbial Pathogens
Family Health
Psychological and Psychosocial Issues
business.industry
Lentivirus
lcsh:R
Organisms
Infant
Biology and Life Sciences
HIV
030112 virology
Focus group
Health Care
Age Groups
Family medicine
People and Places
Africa
Patient Compliance
Population Groupings
lcsh:Q
business
Zdroj: PLoS ONE, Vol 13, Iss 3, p e0192068 (2018)
PLoS ONE
ISSN: 1932-6203
Popis: BACKGROUND In 2013, Uganda adopted a test-and-treat policy for HIV patients 15 years or younger. Low retention rates among paediatric and adolescent antiretroviral therapy (ART) initiates could severely limit the impact of this new policy. This evaluation tested the impact of a differentiated care model called Family Clinic Day (FCD), a family-centered appointment scheduling and health education intervention on patient retention and adherence to monthly appointment scheduling. METHODS We conducted a cluster randomized controlled trial, from October 2014 to March 2015. Forty-six facilities were stratified by implementing partner and facility type and randomly assigned to the control or intervention arm. Primary outcomes included the proportion of patients retained in care at 6 months and the proportion adherent to their appointment schedule at last study period scheduled visit. Data collection occurred retrospectively in May 2015. Six patient focus group discussions and 17 health workers interviews were conducted to understand perspectives on FCD successes and challenges. RESULTS A total of 4,715 paediatric and adolescent patient records were collected, of which 2,679 (n = 1,319 from 23 control facilities and 1,360 from 23 intervention facilities) were eligible for inclusion. The FCD did not improve retention (aOR 1.11; 90% CI 0.63-1.97, p = 0.75), but was associated with improved adherence to last appointment schedule (aOR 1.64; 90% CI 1.27-2.11, p
Databáze: OpenAIRE
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