Acute erythema and edematous skin reaction and ectropion following docetaxel in a patient with non-small cell lung cancer
| Autor: | Esra Adişen, Banu Ozturk, Ali Osman Kaya, Mustafa Benekli, Suleyman Buyukberber, Mustafa Gureli, Emel Yaman, Ramazan Yildiz, Ugur Coskun |
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| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Erythema medicine.medical_treatment Ectropion Antineoplastic Agents Docetaxel Toxicology Carboplatin Carcinoma Non-Small-Cell Lung medicine Edema Humans Chemotherapy integumentary system business.industry Onycholysis Madarosis General Medicine Middle Aged medicine.disease Surgery medicine.anatomical_structure Nail (anatomy) Taxoids Drug Eruptions medicine.symptom business Adverse drug reaction medicine.drug |
| Zdroj: | Cutaneous and Ocular Toxicology. 27:327-331 |
| ISSN: | 1556-9535 1556-9527 |
| DOI: | 10.1080/15569520802431369 |
| Popis: | Docetaxel can cause skin reactions such as hypersensitivity, edema, and erythrodysesthesia syndrome as well as side effects involving the skin, including alopecia, nail onycholysis, nail pigmentation, photosensitivity, scleroderma, and paresthesia. In this case report, a patient was admitted to the hospital with widespread erythematous and edematous eruption in the head, neck, trunk, and lower and upper extremities, erythema around the eyes, and drooping of the lower eyelids that developed about 2 hours after receiving chemotherapy consisting of docetaxel. Use of the Naranjo Adverse Drug Reaction Probability Scale--a method for estimating the probability of adverse drug reactions--indicated a probable relationship between the skin reaction and docetaxel therapy in this patient. Docetaxel-associated skin reactions that are so extensive and severe as to lead to eye madarosis and ectropion are reported rarely in the literature. |
| Databáze: | OpenAIRE |
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