Schistosoma mansoni: analysis of monoclonal antibodies reactive with gut-associated antigens
| Autor: | Van Zeyl Rj, D. Kornelis, J. P. Rotmans, A.M. Deelder, van Dam Gj |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.drug_class Antibodies Helminth Fluorescent Antibody Technique Biology Monoclonal antibody Immunofluorescence Epitope Epitopes Immune system Antigen Antibody Specificity Cricetinae medicine Animals Humans Pan-T antigens Ovum General Veterinary medicine.diagnostic_test Mesocricetus Antibodies Monoclonal General Medicine Schistosoma mansoni biology.organism_classification Isotype Intestines Infectious Diseases Immunoglobulin M Insect Science Antigens Helminth Immunoglobulin G Immunology Parasitology |
| Zdroj: | Parasitology research. 79(1) |
| ISSN: | 0932-0113 |
| Popis: | The analysis of a series of monoclonal antibodies (mAbs) developed in our laboratory against gut-associated antigens of Schistosoma mansoni is described. It was found that mAbs that recognized epitopes of antigens in the gut and on the eggshell were mainly of the IgM isotype; these epitopes are likely to be carbohydrate in composition. Of a number of mAbs that were reactive with antigens important to the human humoral immune response, 75% appeared to be reactive with the circulating cathodic antigen. |
| Databáze: | OpenAIRE |
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