Detection of male genital infection with Chlamydia trachomatis and Neisseria gonorrhoeae using an automated multiplex PCR system (Cobas®Amplicor™)
| Autor: | S P, Higgins, P E, Klapper, J K, Struthers, A S, Bailey, A P, Gough, R, Moore, G, Corbitt, M N, Bhattacharyya |
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| Rok vydání: | 1998 |
| Předmět: |
Male
Sexually transmitted disease Pediatrics medicine.medical_specialty Sexual transmission Population Prevalence Chlamydia trachomatis Dermatology Polymerase Chain Reaction Automation Gonorrhea 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Environmental health Humans Medicine Pharmacology (medical) 030212 general & internal medicine education education.field_of_study 030505 public health biology business.industry Public health Public Health Environmental and Occupational Health virus diseases Chlamydia Infections biology.organism_classification medicine.disease Neisseria gonorrhoeae Infectious Diseases Tanzania Genital Diseases Male Rural area 0305 other medical science business |
| Zdroj: | International Journal of STD & AIDS. 9:21-24 |
| ISSN: | 1758-1052 0956-4624 |
| DOI: | 10.1258/0956462981921594 |
| Popis: | HIV infection continues to occur at high levels in sub-Saharan Africa with adult prevalence often exceeding 20% in some urban areas. Prevalence is lower but steadily increasing in rural areas where most Africans still live. Managing STDs is an increasingly recommended HIV prevention strategy since the results of many epidemiological studies suggest that the presence of STDs may enhance the sexual transmission of HIV. However in many parts of Africa no resources exist with which to properly diagnose STDs. The World Health Organization has therefore been promoting the syndromic management of STDs an approach which provides immediate diagnosis and treatment without expensive and time-consuming laboratory tests. Findings are reported from a study conducted to assess the impact of improved STD services at the primary care level upon the incidence of HIV infection in Mwanza Region northern Tanzania. 6 rural communities received improved STD case management while 6 other communities received only the usual STD services. Communities were matched in pairs based upon pre-intervention STD attendance rates and location. Over the course of 2 years 11632 STD syndromes were treated in the intervention health units. Observed cure rates were high. At baseline HIV-1 prevalence rates in the intervention and control communities were 3.8% and 4.4% respectively. HIV-1 seroconversion was 1.2% over 2 years in the intervention communities and 1.9% in the control communities corresponding to a 42% decreased risk of seroconversion in the intervention communities after adjusting for age sex history of travel baseline STD prevalence and male circumcision. |
| Databáze: | OpenAIRE |
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