Meat consumption reduces the risk of nutritional rickets and osteomalacia

Autor: M.G. Dunnigan, David J Hole, E. Barbara Mawer, Jacqueline L. Berry, J.B. Henderson
Rok vydání: 2005
Předmět:
Zdroj: British Journal of Nutrition. 94:983-991
ISSN: 1475-2662
0007-1145
DOI: 10.1079/bjn20051558
Popis: Endogenous vitamin D deficiency (low serum 25(OH)D3) is a necessary but insufficient requirement for the genesis of vitamin D-deficiency rickets and osteomalacia. The magnitude of the independent contributions of dietary factors to rachitic and osteomalacic risk remains uncertain. We reanalysed two weighed dietary surveys of sixty-two cases of rickets and osteomalacia and 113 normal women and children. The independent associations of four dietary variables (vitamin D, Ca, fibre and meat intakes) and daylight outdoor exposure with rachitic and osteomalacic relative risk were estimated by multivariate logistic regression. Meat and fibre intakes showed significant negative and positive associations respectively with rachitic and osteomalacic relative risk (RR; zero meat intake: RR 29·8 (95 % CI 4·96, 181),PP+0·043). The negative association of meat intakes with rachitic and osteomalacic relative risk was curvilinear; relative risk did not fall further at meat intakes above 60 g daily. Daylight outdoor exposure showed a significant negative association with combined relative risk (RR 0·33 (95 % CI 0·17, 0·66),P
Databáze: OpenAIRE