CMR assessment of right ventricular function in patients with combined pulmonary stenosis and insufficiency after correction of tetralogy of Fallot

Autor: David M. Naeger, Alison K. Meadows, Charles B. Higgins, Maureen P. Kohi, Karen G. Ordovas, Elyse Foster
Rok vydání: 2013
Předmět:
Adult
medicine.medical_specialty
anatomy
Adolescent
pediatrics
Heart disease
Clinical Sciences
Magnetic Resonance Imaging
Cine
Pulmonary insufficiency
heart
Cardiovascular
Postoperative Complications
Clinical Research
Internal medicine
medicine
Humans
Ventricular Function
magnetic resonance imaging
Radiology
Nuclear Medicine and imaging
In patient
Child
Retrospective Studies
Aged
Tetralogy of Fallot
Radiological and Ultrasound Technology
Ventricular function
medicine.diagnostic_test
business.industry
congenital
Magnetic resonance imaging
General Medicine
Middle Aged
Surgical correction
medicine.disease
Pulmonary Valve Insufficiency
Pulmonary Valve Stenosis
Right
Nuclear Medicine & Medical Imaging
Stenosis
Heart Disease
Cine
Ventricular Function
Right
Cardiology
Biomedical Imaging
Radiology
business
Cardiac
Zdroj: Acta radiologica (Stockholm, Sweden : 1987), vol 54, iss 10
Kohi, MP; Ordovas, KG; Naeger, DM; Meadows, AK; Foster, E; & Higgins, CB. (2013). CMR assessment of right ventricular function in patients with combined pulmonary stenosis and insufficiency after correction of tetralogy of Fallot. Acta Radiologica, 54(10), 1132-1137. doi: 10.1177/0284185113491565. UCSF: Retrieved from: http://www.escholarship.org/uc/item/05d927c3
ISSN: 1600-0455
0284-1851
Popis: Background: Tetralogy of Fallot (TOF) is one of the most common types of congenital heart disease and requires prompt surgical correction. Post-correction pulmonary insufficiency (PI) often ensues in adulthood. At times, the PI is accompanied by residual pulmonary stenosis (PS). Little is known regarding right ventricular (RV) function in the setting of combined PS and PI. Purpose: To compare cardiac magnetic resonance (CMR) parameters for the assessment of RV function between patients with combined pulmonary stenosis and pulmonary insufficiency (PSPI) and isolated PI following surgical repair of TOF. Material and Methods: Retrospective review of patients with comparable corrected TOF and similar PI was performed. Seventeen patients (median age, 24 years; range, 10-52 years) had combined PSPI and 30 patients (median age, 30 years; range, 6-70 years) had isolated PI. Cine magnetic resonance (MR) images (Philips Medical Systems, Best, The Netherlands) in the short-axis plane were used to calculate end-systolic, end-diastolic, and stroke volumes (RVESV, RVEDV, RVSV) and to measure RV wall thickness. Velocity-encoded cine MR images were used to measure pulmonary regurgitation fraction (PRF) by calculating the ratio of backward flow and total forward flow, obtained from the main pulmonary flow analysis. Peak pressure gradient across the pulmonary valve was obtained from spectral Doppler echocardiography. Results: RVEF was 51±8% in the PSPI patients and 39±11%, in the patients with isolated PI (P=0.001). Additionally, RV wall thickness was 5.2±0.8mm in the PSPI patients compared to 2.6±0.9mm in the isolated PI patients (P=0.001). RVESVi and RVEDVi were significantly lower (P
Databáze: OpenAIRE
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