Prediction of the presence of renal artery stenosis by calcium scoring of the abdominal aorta
| Autor: | Johannes Petersen, Parinaz Nasseri, Bernhard Glodny, Peter Rehder, Michaela Plaikner, Verena Unterholzner, Christian Koppelstätter |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Aortic Diseases Renal Artery Obstruction Renal artery stenosis Sensitivity and Specificity Statistics Nonparametric Predictive Value of Tests medicine.artery Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Aorta Abdominal Child Aged Retrospective Studies Computed tomography angiography Aged 80 and over Aorta medicine.diagnostic_test business.industry Abdominal aorta Angiography Area under the curve Calcinosis Infant General Medicine Middle Aged medicine.disease Stenosis ROC Curve Child Preschool Cardiology Radiographic Image Interpretation Computer-Assisted Female Tomography X-Ray Computed business Calcification |
| Zdroj: | European Journal of Radiology. 81:1393-1399 |
| ISSN: | 0720-048X |
| Popis: | To establish a method for estimating the probability of renal artery stenosis (RAS) based on the calcium volume score of the aorta (ACS).In a retrospective observation study, CT angiographies acquired on a 64-slice MDCT scanner were analyzed for 1351 patients (female: 531; male 826; mean age 60.9 ± 17.7 years). A volumetric scoring method was used, detecting plaques with a density of more than 600 HU.13.8% of the patients showed a stenosis50%, 4.1% a stenosis70%. The ACS was 0.61 ± 1.01 ml calcium. The sensitivity for detection of RAS50% and RAS80% was 0.9572 and 1.0, respectively. The negative predictive value (NPV) of a lack of calcification for excluding RAS50% and RAS80% was 0.9752 and 1, respectively. As ACS increased, the specificity for RAS50% increased to 0.9390. With an ACS of 0.380 ml, accuracy reached a maximum of 0.6585. ROC analyses yielded an area under the curve of 0.88 (p0.0001). Sensitivity, specificity, NPV and PPV are indicated in relation to the degree of RAS, as well as the diagnostic yield of the method, which is valuable in patients older than 50 years.Due to its extremely high sensitivity and NPV, the ACS is a very useful screening method for RAS. The validity of the method, as well as its diagnostic value is equivalent to that of coronary artery calcium scoring. Lack of calcifications of the aorta renders atherosclerotic RAS highly improbable. |
| Databáze: | OpenAIRE |
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