Correlation of anti-tumour drug resistance with epigenetic regulation
Autor: | Ikuo Konishi, Takuma Hayashi |
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Rok vydání: | 2020 |
Předmět: |
Cancer Research
Antineoplastic Agents Drug development Drug resistance Bioinformatics Epigenesis Genetic 03 medical and health sciences Anti tumour 0302 clinical medicine Neoplasms medicine Humans Epigenetics Selection (genetic algorithm) Ovarian Neoplasms business.industry Cancer medicine.disease Cancer treatment Clinical Practice Cancer therapeutic resistance Editorial Oncology Drug Resistance Neoplasm 030220 oncology & carcinogenesis Female business |
Zdroj: | British Journal of Cancer |
ISSN: | 1532-1827 0007-0920 |
DOI: | 10.1038/s41416-020-01183-y |
Popis: | SummaryDuring treatment, the development of drug-resistant tumours remains an important challenge in cancer treatment. Epigenetic changes have been reported as one of the mechanisms for anti-tumour drug resistance. In clinical practice, a combination of epigenetic-related drugs can be considered as a future selection of cancer therapeutic drugs. |
Databáze: | OpenAIRE |
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