Effects of weight loss from a high-calcium energy-reduced diet on biomarkers of inflammatory stress, fibrinolysis, and endothelial function in obese subjects
| Autor: | Márcia Regina Simas Gonçalves Torres, Antonio Felipe Sanjuliani |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Diet Reducing Endothelium Endocrinology Diabetes and Metabolism medicine.medical_treatment Vascular Cell Adhesion Molecule-1 chemistry.chemical_element Inflammation Calcium Weight loss Internal medicine Plasminogen Activator Inhibitor 1 Weight Loss Fibrinolysis medicine Humans Obesity Endothelial dysfunction Nutrition and Dietetics Cell adhesion molecule business.industry Endothelial function Middle Aged Intercellular Adhesion Molecule-1 medicine.disease Calcium Dietary C-Reactive Protein Endocrinology medicine.anatomical_structure chemistry Female Endothelium Vascular Inflammation Mediators medicine.symptom E-Selectin business Dietary calcium Biomarkers |
| Zdroj: | Nutrition. 29:143-151 |
| ISSN: | 0899-9007 |
| DOI: | 10.1016/j.nut.2012.05.012 |
| Popis: | Objective: Obesity is characterized by chronic subclinical inflammation, which is critical to endothelial dysfunction. Weight loss, induced by lifestyle interventions, is associated with a decline in biomarkers of inflammation and endothelial dysfunction. There is little evidence that high dietary calcium intake may reduce inflammation and improve endothelial function. The purpose of this study was to evaluate the effects of weight loss from a high-calcium energy-reduced diet on biomarkers of inflammation, fibrinolysis, and endothelial function in obese individuals. Methods: In this randomized clinical trial, we analyzed the data from 35 obese adults who lost at least 3% of initial body weight, during a period of 16 wk of energy restriction (� 800 Kcal/d). Individuals were randomized into the following dietary regimens: (1) a high calcium diet (HCD; 1200–1300 mg/d) or (2) a low-calcium diet (LCD |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect