Association between toothbrushing and non-alcoholic fatty liver disease

Autor: Seung Hyun Ko, Kyungdo Han, Ji-Youn Kim, Yu-Bae Ahn, Yong-Moon Park, Gyu-Na Lee, Hyun Chul Song
Rok vydání: 2021
Předmět:
Male
Social Sciences
Biochemistry
Endocrinology
Medical Conditions
Oral Diseases
Sociology
Non-alcoholic Fatty Liver Disease
Risk Factors
Medicine and Health Sciences
Metabolic Syndrome
Alcohol Consumption
Multidisciplinary
Liver Diseases
Fatty liver
Middle Aged
Lipids
Cholesterol
Liver
Medicine
Female
Research Article
Adult
Toothbrushing
medicine.medical_specialty
Alcohol Drinking
National Health and Nutrition Examination Survey
Endocrine Disorders
Science
Oral Medicine
Gastroenterology and Hepatology
Lower risk
Education
Diabetes mellitus
Internal medicine
Republic of Korea
Diabetes Mellitus
medicine
Humans
Periodontitis
Periodontal Diseases
Educational Attainment
Aged
Nutrition
business.industry
Biology and Life Sciences
Odds ratio
medicine.disease
Confidence interval
Diet
Fatty Liver
Metabolic Disorders
Metabolic syndrome
business
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 5, p e0243686 (2021)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0243686
Popis: Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndomes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index ≥60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35 - 0.90) in the group who performed toothbrushing ≥ 3 per day compared to the group that performed toothbrushing ≤ 1 per day. For those with toothbrushing frequency ≤1 per day, the adjusted OR (95% CIs) of NAFLD was 2.27 (1.22-4.23) in smokers and 4.55 (1.98 – 10.44) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency ≥2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients.
Databáze: OpenAIRE
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