Symptoms of sleep disordered breathing in children with craniofacial malformations
| Autor: | Marta Moraleda-Cibrián, Mary Berger, Louise M. O'Brien, Sean P. Edwards, Steven J. Kasten, Steven R. Buchman |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Adolescent Cross-sectional study Craniofacial abnormality Disorders of Excessive Somnolence Audiology Craniofacial Abnormalities Sleep Apnea Syndromes DiGeorge syndrome Intellectual Disability Surveys and Questionnaires Intellectual disability DiGeorge Syndrome Medicine Humans Craniofacial Child Pierre Robin Syndrome business.industry Brachydactyly Snoring Facies New Research medicine.disease respiratory tract diseases Cross-Sectional Studies Neurology Child Preschool Pierre Robin syndrome Sleep disordered breathing Female Neurology (clinical) business Mandibulofacial Dysostosis |
| Zdroj: | Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine. 10(3) |
| ISSN: | 1550-9397 |
| Popis: | The purpose of this study was to investigate the frequency of sleep disordered breathing (SDB) symptoms in a clinical sample of children with congenital craniofacial malformations (CFM) followed at a tertiary medical center and non-selected for sleep problems.Cross-sectional study of 575 children aged 2-18 years followed at the Craniofacial Anomalies Program between March 2007 and May 2011. The Sleep-Related Breathing Disturbance scale of the Pediatric Sleep Questionnaire was used to screen for SDB, snoring, and sleepiness. A cutoff value ≥ 0.33 of the total answered questions identified children with positive screening for SDB symptoms.Overall, 25% of children screened positive for SDB, 28% for snoring, and 20% for sleepiness. In children with non-syndromic CFM, those with Robin sequence had the highest frequency of SDB, snoring, and sleepiness (43%, 44%, and 38%, respectively). In children with syndromic CFM, velocardiofacial/ DiGeorge syndrome had the highest frequency of SDB and sleepiness (48% and 43%, respectively). Children with Treacher Collins had the highest frequency of snoring (83%). The presence of cleft palate was not associated with an increased frequency of SDB symptoms. Nevertheless, children with syndromic CFM, compared to those with non-syndromic CFM, had a higher SDB score (0.27 ± 0.21 vs.0.21 ± 0.19, p = 0.003) and were more likely to have sleepiness (26% vs. 18%, p = 0.05).Congenital craniofacial malformations in children are associated with high risk for SDB symptoms. Our findings should encourage a high index of suspicion for SDB in children with CFM, with a low threshold for further testing and close follow-up.Moraleda-Cibrián M; Edwards SP; Kasten SJ; Berger M; Buchman SR; O'Brien LM. Symptoms of sleep disordered breathing in children with craniofacial malformations. |
| Databáze: | OpenAIRE |
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