Additional B-cell malignancies in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL)

Autor:	Clive S. Zent, Philip J. Meacham, AnnaLynn M. Williams, Danielle Wallace, Nicholas P. Tschernia, Walter Richard Burack, Paul M. Barr, Myla Strawderman, William J. Archibald, Andrea Baran
Rok vydání:	2020
Předmět:	Cancer Research Lymphoma B-Cell Chronic lymphocytic leukemia Lymphocytic lymphoma 03 medical and health sciences 0302 clinical medicine immune system diseases Risk Factors hemic and lymphatic diseases Medicine Humans In patient Genetic risk neoplasms B cell B-Lymphocytes business.industry Incidence Hematology medicine.disease Leukemia Lymphocytic Chronic B-Cell Increased risk medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Diffuse large cell lymphoma Cancer research Hodgkin lymphoma business 030215 immunology
Zdroj:	Leukemialymphoma. 61(7)
ISSN:	1029-2403
Popis:	Family and migration studies suggest a genetic risk of developing chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL). We hypothesized that CLL patients have an increased risk of additional clonally unrelated B-cell malignancies. To test this, we studied 467 CLL patients (2743 person-years (PYs)) at a single institution over 17 years. The incidence rate (IR) of any additional B-cell lymphoid malignancy was 10.9 per 1000 PYs (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd89cb0297f3c9adeb6391af7a2679f3 https://pubmed.ncbi.nlm.nih.gov/32175786 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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