Tuning the Nitric Oxide release from CPO-27 MOFs
| Autor: | Russell E. Morris, Stewart J. Warrender, Morven J. Duncan, Phillip D. Whitfield, Ian L. Megson, Mary K. Doherty, Christopher Kelsall, Damiano Cattaneo |
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| Přispěvatelé: | EPSRC, University of St Andrews. School of Chemistry, University of St Andrews. EaSTCHEM |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Materials science
General Chemical Engineering Doping Nanotechnology NO storage DAS 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Biological effect QD Chemistry 01 natural sciences 0104 chemical sciences Nitric oxide chemistry.chemical_compound chemistry Chemical engineering Relaxation (physics) QD 0210 nano-technology Porcine coronary artery |
| Popis: | The authors gratefully acknowledge the funding of this work from Scottish Enterprise (POC13), the EPSRC (EP/K025112/1), the British Heart Foundation (NH/11/8/29253) and the Royal Society (Brian Mercer Award for Innovation - MI120033). Date of Acceptance: 17/01/2016 Nitric Oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that NO dosage and biological response can be tuned via this approach to suit the requirements of particular applications. Publisher PDF |
| Databáze: | OpenAIRE |
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