Efekat suplementacije propolisom i N-acetilcisteinom na raspodelu lipoproteinskih supklasa i aktivnosti paraoksonaze 1 u osoba sa akutnom respiratornom infekcijom
| Autor: | Milica Miljković, Jelena Janac, Dejan Zujović, Vesna Spasojevic-Kalimanovska, Marija Mihajlovic, Sanja Vujcic, Jelena Vekic, Jasmina Ivanisevic, Natasa Bogavac-Stanojevic, Aleksandra Zeljkovic, Jelena Kotur-Stevuljevic |
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| Rok vydání: | 2020 |
| Předmět: |
030213 general clinical medicine
antioksidanti Clinical Biochemistry Physiology 030209 endocrinology & metabolism medicine.disease_cause Lipoprotein particle smoking akutna respiratorna infekcija lcsh:Biochemistry 03 medical and health sciences n-acetylcysteine 0302 clinical medicine medicine lcsh:QD415-436 2. Zero hunger Original Paper biology medicine.diagnostic_test business.industry pušenje Biochemistry (medical) Paraoxonase Respiratory infection Propolis N-acetylcysteine lipoproteini 3. Good health lipoproteins propolis antioxidants medicine.anatomical_structure N-acetilcistein acute respiratory infection biology.protein Lipid profile business Oxidative stress Respiratory tract Lipoprotein |
| Zdroj: | Journal of Medical Biochemistry, Vol 39, Iss 4, Pp 467-473 (2020) Journal of Medical Biochemistry J Med Biochem Journal of Medical Biochemistry (2020) 39(4):467-473 |
| ISSN: | 1452-8266 1452-8258 |
| Popis: | Background:Propolis and N-acetylcysteine have positiveimpact on respiratory tract health. Also, it has been sug-gested that they have beneficial effects on serum lipid andoxidative stress status, but the available data are limitedand mostly gained from animal models. In this study weevaluated the effects of propolis and N-acetylcysteine sup-plementation (PropoMucil®) on lipid status, lipoproteinsubclasses distribution and paraoxonase 1 activity in sub-jects with acute respiratory infection.Methods:Twenty subjects with acute respiratory infectionwere included. PropoMucil®granules for oral solution (80mg of dry propolis extract and 200 mg of N-acetylcysteine)were administered tree times per day for ten days. Serumlipid profile, paraoxonase 1 activity and low-density andhigh-density lipoprotein size and subclasses distributionwere assessed at baseline and after supplementation.Results:Following ten days of supplementation lipid statusremained unchanged, but a significant increase of low-density lipoprotein particle size and proportion of high-den-sity lipoprotein 3a particles were found (P |
| Databáze: | OpenAIRE |
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