Myocardial infarction and oral contraceptives
| Autor: | M M Kubik, B K Bhowmick |
|---|---|
| Rok vydání: | 1973 |
| Předmět: |
Adult
medicine.medical_specialty Pediatrics Heart disease Myocardial Infarction Hyperlipidemias Physical examination Left coronary artery medicine.artery Diabetes mellitus medicine Humans Myocardial infarction Family history medicine.diagnostic_test business.industry Smoking Age Factors medicine.disease Lipids Surgery Cholesterol Blood pressure Pill Hypertension Female Cardiology and Cardiovascular Medicine business Research Article Contraceptives Oral |
| Zdroj: | Heart. 35:1271-1274 |
| ISSN: | 1355-6037 |
| DOI: | 10.1136/hrt.35.12.1271 |
| Popis: | This report concerns 3 premenopausal women who sustained acute myocardial infarction while taking an oral contraceptive. All were moderate to heavy smokers. The fathers of all had experienced a myocardial infarction after the age of 50 years. One had a slight hypertension while using oral contraceptives and her serum cholesterol and lipids were increased. Case 1 a 38 year old white woman had been taking Ovulen for 4 years. Except for evidence of myocardial infarction physical examination and laboratory tests were within normal limits. She recovered under therapy and oral contraceptives were discontinued. Case 2 was a 27 year old white woman who had been taking Lyndiol for 3 years. Her earlier blood pressure of 150/100 had returned to normal without treatment although she had continued to take the pill. Serum cholesterol triglycerides and lipoproteins were elevated. Coronary arteriography showed generalized narrowing of branches of the left coronary artery. She recovered but continued under treatment. Oral contraceptives were discontinued. Case 3 was a 37 year old white woman who had been taking Gynovlar for the past 5 years. Although the electrocardiogram showed extensive anteroseptal myocardial infaraction she recovered and remains well. Contraceptives were discontinued. Except when hypertension diabetes of lipidaemia are present ischamic heart disease is rare in women at this age. It is thought possible that oral contraceptives may occasionally accelerate thrombogenesis and resulting myocardial infarction with or without associated serum lipid changes especially in those with a family history of other predisposing (causes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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