High rates of methicillin-resistant Staphylococcus aureus colonisation in a Brazilian Intensive Care Unit
| Autor: | Paulo César dos Santos, Humberto Medeiros Barreto, Daniela Reis Joaquim de Freitas, Isabela Ribeiro de Sá Guimarães Nolêto, Daniela Furtado Rodrigues de Andrade, Maria Eliete Batista Moura, Helen Maria da Silva Gomes, Daniele Martins de Sousa Oliveira, Isaniel Pereira de Oliveira, Rosilane de Lima Brito Magalhães, Aline Raquel de Sousa Ibiapina |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
Methicillin-Resistant Staphylococcus aureus 0301 basic medicine medicine.medical_specialty Vancomycin-resistant Staphylococcus aureus medicine.medical_treatment 030106 microbiology Oropharynx Critical Care Nursing medicine.disease_cause law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine Humans Medicine 030212 general & internal medicine Critical condition High rate Cross Infection Infection Control business.industry Middle Aged Staphylococcal Infections medicine.disease Methicillin-resistant Staphylococcus aureus Intensive care unit Colonisation Intensive Care Units Cross-Sectional Studies Staphylococcus aureus Female business Brazil Central venous catheter |
| Zdroj: | Intensive and Critical Care Nursing. 49:51-57 |
| ISSN: | 0964-3397 |
| DOI: | 10.1016/j.iccn.2018.08.003 |
| Popis: | Objective To evaluate the colonisation rate of Staphylococcus aureus in the oropharynx and the insertion site of central venous catheters in intensive care unit patients. Design Cross-sectional study. Setting Brazilian intensive care unit. Measurements Samples were collected from October to December 2015 from the oropharyngeal cavity and central venous catheter insertion site of 110 patients. Samples that presented growth of Staphylococcus aureus were isolated and their sensitivity profiles were tested for several antimicrobials. Findings The study participants (110) were mostly females older than 60 years (53.6%). The mean length of hospitalisation was 15.5 days (±31.3). A total of 188 biological samples were collected: 110 collected from the oropharynx and 78 from the central venous catheter insertion site. A 35% (n = 38/110) S. aureus colonisation rate of the patients was observed in at least one collection site. In the oropharynx alone, a 31% rate (n = 34/110) was found, and a 12.8% rate (n = 10/78) at central venous catheter insertion sites only. MRSA colonisation in the oropharynx or at the central venous catheter occurred in 29 (26.4%) patients and vancomycin resistant Staphylococcus aureus was present in 24 (22.4%) of the patients studied. Patients hospitalised for seven days or more were 4.8 times more likely to be colonised compared to patients hospitalised less than seven days (95% CI = 1.2–28.5). Conclusion The oropharynx and the central venous catheter are important reservoirs of this bacterium that in critical conditions may become pathogenic. The data showed a high degree of resistance of the bacterial populations isolated to different drugs, which may hinder the control of these organisms. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect