Managing HBV in pregnancy. Prevention, prophylaxis, treatment and follow-up: position paper produced by Australian, UK and New Zealand key opinion leaders
| Autor: | Simone I. Strasser, Michelle L. Giles, Susan P. Walker, May-Ling Wong, Miriam T. Levy, Nghi Phung, Suong Le, Scott Bowden, Winita Hardikar, Edward Gane, Meng C. Ngu, Geoff Dusheiko, Ben Cowie, Kumar Visvanathan, Seng Gee Lim, Joe Sasaduesz |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine.disease_cause Antiviral Agents 03 medical and health sciences 0302 clinical medicine Pregnancy Prenatal Diagnosis medicine Humans 030212 general & internal medicine Pregnancy Complications Infectious Referral and Consultation Hepatitis B virus Gynecology Transmission (medicine) business.industry Postpartum Period Vaccination Infant Newborn Gastroenterology Infant Hepatitis B Delivery Obstetric medicine.disease Infectious Disease Transmission Vertical Chronic infection Breast Feeding Family medicine Position paper Female 030211 gastroenterology & hepatology business Breast feeding Postpartum period Follow-Up Studies |
| Zdroj: | Gut. 65:340-350 |
| ISSN: | 1468-3288 0017-5749 |
| Popis: | Hepatitis B during pregnancy presents unique management issues for both the mother and fetus. These include the lack of a current cohesive strategy for treatment and follow-up of mothers and their babies; the uncertain risk of postpartum HBV flares; the lack of randomised trial data on the safety and efficacy of antiviral treatment in pregnancy; the lack of head-to-head studies comparing different antivirals in pregnancy; and the lack of epidemiologic information regarding infection across different populations globally. This position paper provides a comprehensive review of the management of women with HBV infection prior to conception, throughout each stage of pregnancy and postpartum, as well as recommendations and clinical approaches for the follow-up of children born to infected mothers, based on available evidence in the literature and recommendations from international experts. Prevention of perinatal transmission is an important component of global efforts to reduce the burden of chronic HBV since vertical transmission is responsible for most of the chronic infection worldwide. |
| Databáze: | OpenAIRE |
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