Blood coagulation alterations after embolic occlusion of the renal circulation

Autor: L. E. Almgård, Margareta Blombäck, Ulf Norming, Staffan Törngren, Claes R. Nyman
Rok vydání: 1990
Předmět:
Zdroj: Scandinavian journal of urology and nephrology. 24(2)
ISSN: 0036-5599
Popis: Alterations in blood coagulation and fibrinolysis after embolic occlusion of renal adenocarcinoma were investigated in 11 patients. Peripheral vein blood was collected before, 2 hours after and on the first, third and fifth to seventh day after embolization. Five patients had renal vein blood sampling before and 2 hours after embolization. Increased levels of fibrinogen, plasminogen and antiplasmin were found on days 1-3. Antithrombin III showed a slight decrease between days 1 and 3 after embolization. All measured variables were lower in renal vein compared with simultaneous samples from peripheral vein. In renal vein samples, consumption of antiplasmin and antikallikrein was indicated. Fibrinopeptide A (FPA) was increased, with a mean maximum 2 hours after embolization. The findings seemed mainly to monitor acute phase reaction but also activation of blood coagulation and fibrinolysis. Embolization might be used as a human model of coagulation activation and acute phase reaction.
Databáze: OpenAIRE