Subjective sleep quality is associated with disease status in COPD patients. The cross-sectional Greek UNLOCK study

Autor: Despo, Ierodiakonou, Izolde, Bouloukaki, Maria, Kampouraki, Polyvios, Papadokostakis, Ioannis, Poulorinakis, Irene, Lampraki, Polyxeni, Athanasiou, Sophia, Schiza, Ioanna, Tsiligianni
Rok vydání: 2020
Předmět:
Zdroj: Sleep and Breathing. 24:1599-1605
ISSN: 1522-1709
1520-9512
DOI: 10.1007/s11325-020-02039-8
Popis: The association of chronic obstructive pulmonary disease (COPD) severity and related health status with sleep quality remains unclear. We aimed to investigate the association between COPD and sleep quality in the Greek national branch of the UNLOCK cohort. A sample of 257 COPD patients enrolled cross-sectionally from primary care in Greece. Sleep quality was assessed by the COPD and Asthma Sleep Impact Scale (CASIS-7 items) questionnaire (higher score indicates worse sleep quality). We tested for associations of sleep impairment with health status (CAT and mMRC scores), exacerbations, hospitalizations, GOLD 2018 ABCD status, inhaler adherence, frailty, and sense of coherence, adjusting for age, gender, smoking status, and comorbidities. The majority of patients reported uncontrolled symptoms (91% with ≥ 10 CAT or 61% with ≥ 2 mMRC). Mean (SD) age was 65 (12.3) with 79% males. CASIS-7 mean (SD) score was 37.7 (12.9). After adjustments, CASIS was significantly associated with worse health status (e.g., CASIS increased with CAT ≥ 10 [β = 12.53, (95% CI, 6.82, 18.25); p
Databáze: OpenAIRE
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