Second re-irradiation for DIPG progression, re-considering 'old strategies' with new approaches
| Autor: | Andres Morales La Madrid, Antonio Guillén Quesada, Vicente Santa-Maria, Mariona Suñol Capella, Normand Laperriere, Salvador Villà, Eric Bouffet, Ofelia Cruz Martinez, Patricia Puerta Roldán, Carmen de Torres Gomez-Pallete, Alvaro Lassaletta, Jaume Mora |
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| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Oncology Re-Irradiation medicine.medical_specialty medicine.medical_treatment Symptomatic treatment 03 medical and health sciences 0302 clinical medicine Glioma Internal medicine medicine Brain Stem Neoplasms Humans Child business.industry Disease progression General Medicine medicine.disease Surgery Radiation therapy Palliative Therapy 030104 developmental biology Tumor progression Child Preschool 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Disease Progression Female Neurology (clinical) Neurosurgery business |
| Zdroj: | Child's Nervous System. 33:849-852 |
| ISSN: | 1433-0350 0256-7040 |
| DOI: | 10.1007/s00381-017-3352-y |
| Popis: | Diffuse intrinsic pontine glioma (DIPG) is an aggressive infiltrative glioma for which no curative therapy is available. Radiation therapy (RT) is the only potentially effective intervention in delaying tumor progression, but only transiently. At progression, re-irradiation is gaining popularity as an effective palliative therapy. However, at second progression, exclusive symptomatic treatment is usually offered. Here we report two patients with DIPG at second progression who were treated with a second re-irradiation course with good response. Importantly, treatment was well tolerated with no irradiation associated acute toxicity identified. |
| Databáze: | OpenAIRE |
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