Additive manufacturing of nanocellulose based scaffolds for tissue engineering: Beyond a reinforcement filler
| Autor: | Sandra Camarero-Espinosa, Tobias Kuhnt |
|---|---|
| Přispěvatelé: | RS: MERLN - Complex Tissue Regeneration (CTR), CTR |
| Rok vydání: | 2021 |
| Předmět: |
Scaffold
Filler (packaging) Materials science cellulose nanomaterial Polymers and Plastics Biocompatibility Additive manufacturing extracellular matrix mechanical-properties POLYMER NANOCOMPOSITES Biocompatible Materials Nanotechnology cell-adhesion 02 engineering and technology scaffold 010402 general chemistry 01 natural sciences Cell Line Nanocellulose chemistry.chemical_compound Tissue engineering STRESS-TRANSFER CARTILAGE Materials Chemistry Humans Cellulose ELASTIC-MODULUS Nanocomposite Tissue Scaffolds bacterial cellulose Organic Chemistry Cell Differentiation differentiation 021001 nanoscience & nanotechnology Nanostructures 0104 chemical sciences printing chemistry YOUNGS MODULUS Bacterial cellulose Surface modification 0210 nano-technology Biofabrication |
| Zdroj: | Carbohydrate Polymers, 252:117159. ELSEVIER SCI LTD Carbohydrate Polymers |
| ISSN: | 0144-8617 |
| DOI: | 10.1016/j.carbpol.2020.117159 |
| Popis: | Cellulose nanomaterials (CNMs) have attracted great attention in the last decades due to the abundance of the biopolymer, the biorenewable character and the outstanding mechanical properties they account for. These, together with their biocompatibility makes them ideal candidates for tissue engineering (TE) applications. Additive manufacturing is an ideal biofabrication approach for TE, providing rapid and reliable technologies to produce scaffolds aimed for the guidance of host or implanted cells to form functional tissues. However, the control of parameters at the nanoscale that regulate cellular functions such as proliferation and differentiation remain challenging. This review article presents the latest advances in the use of CNMs as platforms to guide cellular functions in additive manufactured scaffolds. Special attention is given to functionalization routes, methods to exploit them as topographical cues and to improve the local mechanical properties together with the resulting cell-CNM interactions. |
| Databáze: | OpenAIRE |
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