Prevalence, multimodality imaging characterization, and mid-term prognosis of quadricuspid aortic valves: an analysis of eight cases, based on 160 004 exams performed during 12 years in a tertiary care hospital
Autor: | Nuno Dias Ferreira, Rita Faria, Gustavo Pires-Morais, Ricardo Ladeiras-Lopes, Ricardo Fontes-Carvalho, Alberto Rodrigues, Pedro Braga, Ana Manuel, Ana Batista, Francisco Sampaio, Carlos Gonçalves, Fernando Gonçalves, Wilson Ferreira, José M. C. Ribeiro, Ricardo Ferraz, Madalena Teixeira, Mónica Carvalho |
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Rok vydání: | 2021 |
Předmět: |
Adult
Male Aortic valve medicine.medical_specialty Heart disease Heart malformation Aortic Valve Insufficiency Regurgitation (circulation) 030204 cardiovascular system & hematology Tertiary Care Centers 03 medical and health sciences 0302 clinical medicine Interquartile range Prevalence Humans Medicine Radiology Nuclear Medicine and imaging Retrospective Studies business.industry General Medicine Middle Aged Prognosis medicine.disease Stenosis Quadricuspid aortic valve medicine.anatomical_structure 030228 respiratory system Quadricuspid Aortic Valve Aortic Valve Female Radiology Abnormality Cardiology and Cardiovascular Medicine business |
Zdroj: | European Heart Journal - Cardiovascular Imaging. 22:765-776 |
ISSN: | 2047-2412 2047-2404 |
Popis: | Aims Quadricuspid aortic valve (QAV) is a rare abnormality, which may cause aortic regurgitation (AR) requiring surgical intervention in some patients. The characteristics associated with aortic valve functional degeneration in patients with QAV are still unknown. The aim of this study is to describe QAV prevalence, characterize the disease by multimodality imaging, evaluate predictors of severe AR, and assess mid-term prognosis. Methods and results Retrospective search in imaging exams database of one tertiary centre, for patients diagnosed with QAV between January 2007 and September 2019. QAV was characterized by cardiac computed tomography, transthoracic/transoesophageal echocardiography, and cardiac magnetic resonance. A total of 160 004 exams were reviewed and eight patients with QAV were identified (50% men, mean age 53.5 ± 10.7 years). The prevalence of QAV was 0.005%. During a median follow-up of 52 months (interquartile range 16–88), there were no deaths. Seven patients (88%) had pure AR (three severe, one moderate, and three mild) and one patient (12%) had moderate AR and moderate aortic stenosis. Three patients (38%) with severe AR underwent valve surgery (two replacements and one repair). Analysis of predictors of severe AR was not statistically significant. Conclusion QAV is a rare congenital cardiac defect, with a prevalence of 0.005% in our study. Its predominant functional abnormality was regurgitation and about one-third of the patients required aortic valve surgery. Multimodality imaging may play a pivotal role in assessing patients with QAV with significant valve dysfunction or associated congenital heart disease and improve their treatment strategy. |
Databáze: | OpenAIRE |
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