Sarcoidosis presenting as antinuclear antibody positive glomerulonephritis
| Autor: | Dennis W. Boulware, M C Soto-Aguilar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1988 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Mediastinal lymphadenopathy Anti-nuclear antibody Sarcoidosis Immunology Lupus nephritis General Biochemistry Genetics and Molecular Biology Diagnosis Differential Glomerulonephritis Rheumatology immune system diseases medicine Immunology and Allergy Humans skin and connective tissue diseases business.industry Interstitial lung disease medicine.disease Lupus Nephritis stomatognathic diseases Antibodies Antinuclear Female Differential diagnosis business Nephrotic syndrome Research Article |
| Popis: | A 43 year old woman who initially presented with the nephrotic syndrome, glomerulonephritis, and antinuclear antibodies (ANAs) was given the diagnosis of systemic lupus erythematosus (SLE). One year later the patient developed progressive subcutaneous nodules on her forearms, with histopathology of non-caseating granulomas. Further evaluation of the patient showed mediastinal lymphadenopathy and interstitial lung disease with numerous granulomas, establishing the diagnosis of sarcoidosis. The presence of autoimmune antibodies and glomerulonephritis has been reported in sarcoidosis, but this case is believed to be the first in which both glomerulonephritis and ANAs are present in a sarcoid patient. |
| Databáze: | OpenAIRE |
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