Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010–2012

Autor: Sergio Araujo, Barbara M. Stryjewska, David M. Scollard, Diana L. Williams
Rok vydání: 2018
Předmět:
0301 basic medicine
folP1
Epidemiology
Biopsy
lcsh:Medicine
Leprostatic Agents
Drug resistance
Dapsone
Clofazimine
0302 clinical medicine
bacteria
Mycobacterium leprae
Skin
biology
American Samoa
Infectious Diseases
Leprosy
Rifampin
medicine.drug
Microbiology (medical)
medicine.medical_specialty
030231 tropical medicine
030106 microbiology
Leprostatic agent
Microbial Sensitivity Tests
dapsone resistance
National Hansen’s Disease Programs
Drug Administration Schedule
lcsh:Infectious and parasitic diseases
Resistance in Leprosy Patients Originally from American Samoa
United States
2010–2012
03 medical and health sciences
Antibiotic resistance
Drug Resistance
Bacterial
Research Letter
medicine
Humans
lcsh:RC109-216
antimicrobial resistance
business.industry
lcsh:R
medicine.disease
biology.organism_classification
Dermatology
United States
tuberculosis and other mycobacteria
National Hansen Disease Program
American samoa
Genes
Bacterial
Mutation
business
rpoB
Zdroj: Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 24, Iss 8, Pp 1584-1585 (2018)
ISSN: 1080-6059
1080-6040
DOI: 10.3201/eid2408.180033
Popis: Skin biopsies from US leprosy patients were tested for mutations associated with drug resistance. Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients. No resistance was observed in patients from other origins. The high rate of dapsone resistance in patients from American Samoa warrants further investigation.
Databáze: OpenAIRE
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