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Background: Different MRI parameters have been studied for evaluating thyroid nodules. Diffusion-weighted imaging (DWI) and T2 imaging sequences with considerable efficacy in evaluating soft tissue tumors merit further assessment for thyroid nodules investigation.Method: In this study, patients with thyroid nodules indicative of fine-needle aspiration and cytology (FNAC) underwent MR imaging studies. The T2 signal intensity(SI), T2 signal intensity ratio (SIR), Z value, and apparent diffusion coefficient (ADC) values of the thyroid nodule were obtained for every patient. Regarding the FNAC results, the nodules were divided into malignant and benign groups. The two groups' MRI parameters were compared using a two samples independent t-test and the cut-off values estimated by analyzing the receiver operating characteristics plot.Results: The T2 values, SIR, Z values, and ADC values were significantly higher in the benign group than malignant. The cut-off points of 230 (AUC= 0.759), 3.38 (AUC=0.754), 37(AUC=0.759), and 1.73(AUC=.690) were obtained for T2values, SIR, Z value, and ADC values, respectively.Conclusion: T2 values, SIR, Z values, and ADC values are reliable parameters in discriminating benign from malignant thyroid nodules, and cut-off points of 230, 3.38, 37, and 1.73 could be reliable cut-off points for each parameter, respectively. However, further studies with a larger sample size are needed to confirm these findings. |
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