Desmoplastic infantile ganglioglioma
| Autor: | Randall D. Craver, Joseph Nadell, James S. Nelson |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Head size
Male Pathology medicine.medical_specialty Virchow robin spaces Desmoplastic infantile ganglioglioma Biology Pathology and Forensic Medicine Ganglioglioma 03 medical and health sciences 0302 clinical medicine Tubulin medicine Humans Neurons 030219 obstetrics & reproductive medicine medicine.diagnostic_test Brain Neoplasms Perineuronal Satellitosis Infant Magnetic resonance imaging Subtotal Resection General Medicine medicine.disease Immunohistochemistry Magnetic Resonance Imaging Neoplasm Proteins 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Synaptophysin biology.protein Microtubule-Associated Proteins Follow-Up Studies |
| Zdroj: | Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2(6) |
| ISSN: | 1093-5266 |
| Popis: | We present the clinical, anatomic, and laboratory findings in a 4-month-old child with desmosplastic infantile ganglioglioma. Microtubule-associated protein-2 (AP18) and neuron-specific B-tubulin (TUJ-1) were more sensitive in detecting immature neural elements than synaptophysin. Despite the immature neuroblastic component, focal intermediate proliferation indices, microinvasion, presence of secondary features (extension into Virchow Robin spaces, perineuronal satellitosis), and subtotal resection, the child has done well, with striking improvement of the magnetic resonance imaging (MRI) image, head size improvement, no tumor recurrence, and minimal neurological deficits. |
| Databáze: | OpenAIRE |
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