Non-curative treatment of patients with oral tongue squamous-cell carcinoma

Autor: Aaro Haapaniemi, Tiina Saarto, Antti Mäkitie, L. Grönholm, Reidar Grénman, Rayan Mroueh, Tuula Salo
Přispěvatelé: Department of Oral and Maxillofacial Diseases, Clinicum, HUS Head and Neck Center, Department of Ophthalmology and Otorhinolaryngology, Department of Surgery, Department of Oncology, University Management, HUS Comprehensive Cancer Center, HUSLAB
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Palliative care
medicine.medical_treatment
0302 clinical medicine
NECK-CANCER
Quality of life
030223 otorhinolaryngology
Head and neck cancer
Finland
DOCETAXEL
Tongue cancer
education.field_of_study
Palliative Care
General Medicine
Middle Aged
3. Good health
Tongue Neoplasms
Palliation
Death
Survival Rate
Docetaxel
030220 oncology & carcinogenesis
SURVIVAL
Female
RADIOTHERAPY
medicine.drug
Adult
medicine.medical_specialty
REFUSAL
3122 Cancers
Population
Clinical Decision-Making
CANCER-PATIENTS
CISPLATIN
03 medical and health sciences
PERCUTANEOUS ENDOSCOPIC GASTROSTOMY
Internal medicine
medicine
Chemotherapy
Humans
HEAD
education
Head & Neck
Survival analysis
Aged
Neoplasm Staging
Retrospective Studies
business.industry
Squamous Cell Carcinoma of Head and Neck
medicine.disease
Survival Analysis
Radiation therapy
Otorhinolaryngology
End of life
Surgery
business
Zdroj: European Archives of Oto-Rhino-Laryngology
ISSN: 1434-4726
0937-4477
Popis: PurposeLate-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival.MethodsAll patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005-2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan-Meier method in this population-based study.ResultsEighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7months (median 2 and range 0-26).ConclusionsDue to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.
Databáze: OpenAIRE
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