| Autor: |
M. Coroama, M.C. Leneveu-Duchemin, S. Tozer, Barbara Hall, C. McNamara, B. Safford, W. Steiling, Michael J. Gibney |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 45(11) |
| ISSN: |
0278-6915 |
| Popis: |
Access to reliable exposure data is essential to evaluate the toxicological safety of ingredients in cosmetic products. This study was carried out by European cosmetic manufacturers acting within the trade association Colipa, with the aim to construct a probabilistic European population model of exposure. The study updates, in distribution form, the current exposure data on daily quantities of six cosmetic products. Data were collected using a combination of market information databases and a controlled product use study. In total 44,100 households and 18,057 individual consumers in five European countries provided data using their own products. All product use occasions were recorded, including those outside of home. The raw data were analysed using Monte Carlo simulation and a European Statistical Population Model of exposure was constructed. A significant finding was an inverse correlation between frequency of product use and quantity used per application for body lotion, facial moisturiser, toothpaste and shampoo. Thus it is not appropriate to calculate daily exposure to these products by multiplying the maximum frequency value by the maximum quantity per event value. The results largely confirm the exposure parameters currently used by the cosmetic industry. Design of this study could serve as a model for future assessments of population exposure to chemicals in products other than cosmetics. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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