Effect of sialoadenectomy on the carriage of Candida albicans in the mouths of rats
| Autor: | Antonio Olavo Cardoso Jorge, Crispian Scully, O P de Almeida, Marilda Aparecida Gonçalves Totti |
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| Rok vydání: | 1993 |
| Předmět: |
Male
Cancer Research Saliva Physiology Biology Xerostomia Salivary Glands Pathology and Forensic Medicine stomatognathic system Candidiasis Oral Surgical removal Major Salivary Gland Candida albicans medicine Animals Rats Wistar Mouth Salivary gland biology.organism_classification Corpus albicans Rats stomatognathic diseases Disease Models Animal medicine.anatomical_structure Carriage Otorhinolaryngology Immunology Periodontics Oral Surgery Carrier effect |
| Zdroj: | Journal of oral pathologymedicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 22(3) |
| ISSN: | 0904-2512 |
| Popis: | Xerostomia provoked in rats by surgical removal of the major salivary glands significantly increased oral carriage of Candida albicans. Five weeks after 3 oral inoculations of 10(8) CFU, C. albicans were found in the mouths in 50% of normal animals but after 8 weeks in none. In xerostomic rats, 100% had oral C. albicans after 5 weeks and after 18 weeks, 66.6% still harboured yeasts. Over the whole experimental period the amount of C. albicans was greater in the mouths of sialoadenectomized than in normal rats. |
| Databáze: | OpenAIRE |
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