Planarity of benzoylthiocarbazate tuberculostatics. IV. Polymorphs of N′-(1,3-dithiolan-2-ylidene)-4-nitrobenzohydrazide
| Autor: | Katarzyna Gobis, Małgorzata Szczesio, Andrzej Olczak, Marek L. Główka |
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| Rok vydání: | 2017 |
| Předmět: |
biology
Chemistry Intermolecular force Crystal structure 010402 general chemistry 010403 inorganic & nuclear chemistry Condensed Matter Physics biology.organism_classification 01 natural sciences Planarity testing 0104 chemical sciences Inorganic Chemistry Mycobacterium tuberculosis Crystallography Polymorphism (materials science) Materials Chemistry Molecule Physical and Theoretical Chemistry |
| Zdroj: | Acta Crystallographica Section C Structural Chemistry. 73:797-802 |
| ISSN: | 2053-2296 |
| DOI: | 10.1107/s2053229617012566 |
| Popis: | The search for new tuberculostatics is important considering the occurrence of drug-resistant strains of Mycobacterium tuberculosis. Three polymorphs of N′-(1,3-dithiolan-2-ylidene)-4-nitrobenzohydrazide (a potentially tuberculostatic agent), C10H9N3O3S2, denoted (I1), (I2) and (I3), and the monohydrate of this compound, C10H9N3O3S2·H2O, (I4), have been characterized by single-crystal X-ray diffraction. The conformations of the molecules in all these structures are very similar. Structures (I1), (I2) and (I3) provide an example of packing polymorphism resulting from different intermolecular interactions. |
| Databáze: | OpenAIRE |
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