Small cell carcinoma of the cervix complicated by syndrome of inappropriate antidiuretic hormone secretion: a case report
| Autor: | Su-Fen Zhao, Cai-Fu Zhao, Ze-Qing Du |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Medicine (General) hyponatremia Vasopressins Uterine Cervical Neoplasms Case Report electrolyte Cervix Uteri Neuroendocrine tumors chemotherapy Biochemistry Small-cell carcinoma Gastroenterology Inappropriate ADH Syndrome 03 medical and health sciences 0302 clinical medicine R5-920 Small cell carcinoma of the cervix Internal medicine medicine Humans Carcinoma Small Cell syndrome of inappropriate antidiuretic hormone secretion Cervix Cervical cancer business.industry Biochemistry (medical) Cell Biology General Medicine medicine.disease Hypertonic saline Menopause 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis Syndrome of inappropriate antidiuretic hormone secretion Female Neoplasm Recurrence Local business Hyponatremia neuroendocrine tumor |
| Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 49 (2021) |
| ISSN: | 1473-2300 0300-0605 |
| Popis: | Small cell carcinoma of the cervix is a rare malignant tumor in the clinical setting. Clinical manifestations of this tumor are mostly similar to those of normal types of cervical cancer. Small cell carcinoma of the cervix only shows symptoms of neuroendocrine tumors, such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). Most of the hyponatremia caused by SIADH can be managed after removal of the cause. Hyponatremia is a predictor of poor prognosis and can be used as an indicator of partial recurrence. We report a case of small cell carcinoma of the cervix complicated by SIADH. Our patient presented with irregular vaginal bleeding after menopause. After one cycle of chemotherapy, there was trembling of the limbs, and a laboratory examination showed low Na+ and low Cl− levels. After limited water intake, intravenous hypertonic saline, and intermittent diuretic treatment, the patient’s blood Na+ levels returned to normal. After a radical operation, the above-mentioned symptoms disappeared. |
| Databáze: | OpenAIRE |
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