Cyclic AMP, adrenaline and noradrenaline in plasma during surgery
| Autor: | S. Nistrup Madsen, T. Vester-Andersen, Claus Christiansen, F. Fog-Møller, Allan Engquist |
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| Rok vydání: | 1978 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Epinephrine Hysterectomy Fight-or-flight response Norepinephrine (medication) Norepinephrine Stress Physiological Internal medicine medicine Cyclic AMP Postoperative phase Endocrine system Humans Skin incision business.industry Surgical procedures Surgery Endocrinology Surgical Procedures Operative Plasma concentration Female business medicine.drug |
| Zdroj: | The British journal of surgery. 65(3) |
| ISSN: | 0007-1323 |
| Popis: | Plasma concentrations of cyclic AMP, adrenaline and noradrenaline were measured in 6 patients undergoing hysterectomy from before induction of anaesthesia to 6 h after skin incision. Noradrenaline did not vary significantly during the observation period, whereas cyclic AMP and adrenaline increased after skin incision. A significant correlation was found between plasma concentrations of cyclic AMP and adrenaline (r = 0.84, P < 0.01), suggesting that the latter is responsible for the increase in plasma cyclic AMP which is observed in relation to surgical procedures. Peak concentrations of cyclic AMP and adrenaline were seen in the early postoperative phase. This indicates that the most pronounced acute endocrine stress response to surgery of moderate severity occurs after termination of anaesthesia. |
| Databáze: | OpenAIRE |
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